
October 12–14, 2026
Agenda
Schedule may be subject to change. Please refer to the final program on-site.
Day 1 · Monday, October 12, 2026
Morning Session
- 08:00–08:30Registration & Check-in
- 08:30–08:35Dean of MEDWelcome Address
- 08:35–08:40Brian KobilkaSymposium Opening AddressNobel Laureate in Chemistry 2012
- 08:40–09:20Alice TingEnzyme-based technologies for mapping and manipulating signaling networks in living cellsStanford UniversityHost: Goran Stjepanovic
- 09:20–10:00Eric XuFirst Principles-Based Drug Design: A Pulsatile FXR Activator as a First-in-Class Treatment for Bile Acid-Related Liver Diseases and ObesityShanghai Institute of Materia Medica, Chinese Academy of SciencesHost: Goran Stjepanovic
- 10:00–10:40Qiang SuUnveiling the Hidden World of Immunoreceptors Through the Structures of Their Transmembrane DomainsShenzhen Medical Academy of Research and TranslationHost: Goran Stjepanovic
- 10:40–10:50Tea Break
- 10:50–11:30Yung Hou WongFunctional Dissection of Receptor-G Protein Promiscuity via Acute Gα Subunit Expression PerturbationHong Kong University of Science and TechnologyHost: Guodong He
- 11:30–12:10Peng ChenTargeted protein degradation in the transmembrane and extracellular spaceShenzhen Bay Laboratory / Peking UniversityHost: Guodong He
- 12:10–12:40Richard YeGPCR regulation of innate immunity and inflammationThe Chinese University of Hong Kong, Shenzhen · Kobilka Institute of Innovative Drug DiscoveryHost: Guodong He
- 12:40–13:25Lunch & Poster session
Afternoon Session
- 13:25–13:30Session Opening
- 13:30–14:10Hideaki KatoStructure, Function, and Physiology of Vasopressin-to-Oxytocin CrosstalkThe University of TokyoHost: Hongli Hu
- 14:10–14:50Jiang XiaPhase-Separated Molecular Coacervates for Cytosolic Delivery and ImmunotherapiesThe Chinese University of Hong KongHost: Hongli Hu
- 14:50–15:30Zhou-Feng ChenThe role of GPCRs in somatosensationShenzhen Medical Academy of Research and TranslationHost: Hongli Hu
- 15:30–15:40Tea Break
- 15:40–16:20Chang-Yu HsiehGenerative AI for Intelligent Drug DesignZhejiang UniversityHost: Xue Guo
- 16:20–17:00Shujia ZhuAtomic Insights into Native NMDA Receptor Diversity in the BrainSouthern University of Science and TechnologyHost: Xue Guo
- 17:00–17:30Yang DuDrug Discovery on human alpha2A adrenergic receptorThe Chinese University of Hong Kong, Shenzhen · Kobilka Institute of Innovative Drug DiscoveryHost: Xue Guo
Day 2 · Tuesday, October 13, 2026
Morning Session
- 08:25–08:30Session Opening
- 08:30–09:10Grégory ScherrerFunctional Organization of GPCR Signaling in Pain and Addiction Neural CircuitsThe University of North Carolina at Chapel HillHost: Bing Cao
- 09:10–09:50Xiaojing PanFrom structure to therapy: targeting the substrate-binding pocket of GLUT9 for anti-hyperuricemia drug discoveryShenzhen Medical Academy of Research and TranslationHost: Bing Cao
- 09:50–10:30Zhen YanUnlocking the Gateway to Chloroplast Protein ImportWestlake UniversityHost: Bing Cao
- 10:30–10:40Tea Break
- 10:40–11:20Ruobing RenTargeting S1P signaling for endothelial protectionFudan UniversityHost: Xue Guo
- 11:20–12:00Jian HuangStructural Pharmacology of Voltage-Gated Ion ChannelsShenzhen Medical Academy of Research and TranslationHost: Xue Guo
- 12:00–12:30Goran StjepanovicStructural basis for regulation of endosomal actin polymerization by the WASH complexThe Chinese University of Hong Kong, Shenzhen · Kobilka Institute of Innovative Drug DiscoveryHost: Xue Guo
- 12:30–13:25Lunch & Poster session
Afternoon Session
- 13:25–13:30Session Opening
- 13:30–14:10TBDTBDHost: Yang Du
- 14:10–14:50Long GuiVisualizing the in situ Architecture of Macromolecules from patients' tissuesShenzhen Medical Academy of Research and TranslationHost: Yang Du
- 14:50–15:30Ye XiangEngineering viral glycoproteins for vaccine developmentTsinghua UniversityHost: Yang Du
- 15:30–15:40Tea Break
- 15:40–16:20Hee-Jung ChoiStructure-guided design of peptide ligands with NPY receptor subtype selectivitySeoul National UniversityHost: Bing Cao
- 16:20–17:00Jian YangTCM-based ion channel drug discoveryShenzhen Medical Academy of Research and TranslationHost: Bing Cao
- 17:00–17:30Guodong HeA TM7 conformational switch governs GPCR transducer selectivityThe Chinese University of Hong Kong, Shenzhen · Kobilka Institute of Innovative Drug DiscoveryHost: Bing Cao
Day 3 · Wednesday, October 14, 2026
Morning Session
- 08:25–08:30Session Opening
- 08:30–09:10Asuka InoueGPCR signaling regulation by membrane nanodomainsKyoto UniversityHost: Hongli Hu
- 09:10–09:50Jun XuAllosteric Regulation of GPCR Signaling by Ligand-Stabilized HomodimerizationSouthern University of Science and TechnologyHost: Hongli Hu
- 09:50–10:30Peilong LuDe novo design of functional transmembrane proteins for signal sensing and responseWestlake UniversityHost: Hongli Hu
- 10:30–10:40Tea Break
- 10:40–11:20Peter GmeinerStructure-based development of functionally selective GPCR agonistsFriedrich-Alexander UniversityHost: Richard Ye
- 11:20–12:00Xiangyu LiuTowards Understanding of GPCR Biased SignalingTsinghua UniversityHost: Richard Ye
- 12:00–12:40Brian KobilkaThe role of protein dynamics in GPCR signalingStanford UniversityHost: Richard Ye
